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Progesterone is one of the most important hormones in the human body, yet it is also one of the most misunderstood. For decades it has been overshadowed by confusion around synthetic progestins, misconceptions about hormone therapy, and a tendency to reduce hormones to overly simple narratives. As a result, many physicians rarely consider progesterone outside of fertility or pregnancy, despite its broad effects on the brain, metabolism, inflammation, and tissue health. Progesterone is not a rare
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