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Amniocentesis – Key Facts Every Nurse Must Know What it is A diagnostic procedure performed from 15–20 weeks gestation involving transabdominal aspiration of 15–20 mL of amniotic fluid under continuous ultrasound guidance. Primary Indications - Prenatal genetic diagnosis (karyotyping, microarray, single-gene testing) - Fetal lung maturity assessment (L/S ratio, lamellar body count) - Diagnosis of intra-amniotic infection (Gram stain, culture, PCR) - Evaluation of severe rhesus isoimmunisation (b
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