Compare and contrast the roles of DNA polymerase I and DNA ligase in DNA replication. a. DNA polymerase I removes the RNA primers from the developing copy of DNA. DNA ligase seals the ends of the new segment, especially the Okazaki fragments. b. DNA polymerase I adds the RNA primers to the already developing copy of DNA. DNA ligase separates the ends of the new segment, especially the Okazaki fragments. c. DNA polymerase I seals the ends of the new segment, especially the Okazaki fragments. DNA