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Dec 17, 2025 · Background Selnoflast is an inhibitor of inflammasomes containing NLRP3, or nod-like receptor family, pyrin domain-containing protein 3. Inflammasomes are multiprotein, cytosolic …

Jul 1, 2025 · Arimoclomol is a hydroxylamine derivative, one of a group of compounds that act as co-inducers of heat-shock protein expression. In preclinical work, arimoclomol reduced symptoms and …

Jun 6, 2025 · Background Troculeucel is an immunotherapy consisting of a patient’s own natural killer cells that have been isolated, expanded in the lab, and re-infused. The cells are not genetically …

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Engensis delivers HGF to muscle, not the central nervous system. Injection of the plasmid into the hind limb muscles of rabbits or mice caused detectable HGF expression for about two weeks, with peak …

Jan 30, 2025 · Summary APPPS1 mice contain human transgenes for both APP bearing the Swedish mutation and PSEN1 containing an L166P mutation, both under the control of the Thy1 promoter. In …

May 28, 2020 · Kynmobi’s active compound is apomorphine, which results from the chemical decomposition of morphine. It does not contain morphine or bind to opioid receptors. Apomorphine is …

Mar 10, 2022 · In trials, the most frequent side effects were euphoria, dizziness, sleepiness, nausea and vomiting, abnormal thinking, paranoia, and abdominal pain. Risks of dronabinol in older people …