Computational models of the glucoregulatory system constitute a powerful tool for preclinical evaluation and mechanistic insight into therapeutics. However, in the case of diabetes, there is a dearth ...

Major challenges remain to precisely detect low-abundance proteins rapidly and cost-effectively from diverse biofluids. Here, we present a gold nanoparticle (AuNP)-supported, rapid electronic ...

The high clinical failure rate of small-molecule drugs is inarguably attributable to the lack of reliable predictions of chemical structure–efficacy–toxicity relationships that are applicable to ...

Low loose bulk density, a characteristic commonly observed in large accumulations of needle-like crystals, has caused numerous issues in both production processes and daily life. Antisolvent ...

Metal-ammine (NH3) and metal-amide (NH2) species are common intermediates in ammonia oxidation, typically designed with weak N–H bonds to facilitate the sequential breakage of N–H bonds. Since the ...

We report an iridium-catalyzed asymmetric formal [3 + 2] cycloaddition between carboxylic acids and vinylcyclopropanes to access highly enantioenriched tetrahydrofurans. This reaction proceeds under ...

The rapid increase in plastic production has led to significant environmental challenges due to the accumulation of nondegradable plastic waste, underscoring the urgent need for sustainable ...

Halogen atom transfer (XAT) and single electron transfer (SET) have emerged as versatile tools for the generation of aryl radicals. The intrinsic reactivity of these methods is governed by bond ...

Controllable conversion of reactants to desired products in electrocatalytic reactions is of inherent significance but faces fundamental challenges, such as the oxidation upgrading of polyhydric ...

ConspectusPhotovoltaics (PVs) are currently the most economical and location-independent source of electricity generation, and their demand is growing rapidly as a sustainable renewable energy source.

Colloidal particles can co-assemble into multicomponent ordered superstructures, with their properties determined by the individual building blocks. Here, we demonstrate that covalent organic ...

Fruit spoilage has led to significant food waste and economic losses and poses risks to human health. Currently, widely used plastic bag preservation techniques exhibit limited effectiveness, often ...