Computational models of the glucoregulatory system constitute a powerful tool for preclinical evaluation and mechanistic insight into therapeutics. However, in the case of diabetes, there is a dearth ...

The high clinical failure rate of small-molecule drugs is inarguably attributable to the lack of reliable predictions of chemical structure–efficacy–toxicity relationships that are applicable to ...

We herein disclose a mild and efficient cadmium-catalyzed domino reaction for accessing 1,6-enynes via a sequential A 3 -coupling/1,5-hydride transfer/hydrolysis/A 3 -coupling. This method ...

This work studies the friction and wear behaviors of chromium (hard material) and crystalline cellulose (soft material) under water lubrication considering the loading and sliding velocity on friction ...

Protein–ligand binding affinity may be affected by protein mutations, especially point mutations occurring within the binding site, which may indirectly contribute to interindividual differences in ...

Efficient strategies (degradation or recycling) for converting multifarious plastic wastes are imperative due to the resulting detriments to the environment and human life. With this in mind, the ...

Low loose bulk density, a characteristic commonly observed in large accumulations of needle-like crystals, has caused numerous issues in both production processes and daily life. Antisolvent ...

ConspectusPhotovoltaics (PVs) are currently the most economical and location-independent source of electricity generation, and their demand is growing rapidly as a sustainable renewable energy source.

A method for C(sp3)–C(sp3) cross-coupling of amines is described. Primary amines are converted to 1,2-dialkyldiazenes by treatment with O-nosylhydroxylamines in the presence of atmospheric oxygen.

Carbon dots (CDs) with circularly polarized long afterglow (CPLA) properties have received increasing attention as a cutting-edge research field. However, because the CDs with both long afterglow and ...

Soy protein is widely known to have serum triglyceride (TG) and cholesterol-lowering effects associated with a reduced risk of cardiovascular disease. Recent studies highlighted that the extension ...

In view of their exceptional approach, excellent inherent biocompatibility and biodegradability properties, and interaction with the local extracellular matrix, protein-based polymers have received ...