The prediction of protein structure with the use of artificial intelligence and machine learning (AI–ML) is poised to transform how and when three-dimensional (3D) biostructure information is used in ...

Proteins are made of amino acid chains, or polypeptides. Amino acids have a basic backbone made of an amino group and a carboxyl group, and differ in their side-chains. These polypeptide chains of ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

When he wasn’t playing the viola or sailing around the Chesapeake Bay during the early 1950s, National Institutes of Health scientist Christian Anfinsen was hard at work in the lab trying to ...

Marcelo Sousa, a biochemist at the University of Colorado Boulder, had spent ten years trying to crack a particularly tricky puzzle. Sousa and his team had collected reams of experimental data on a ...

The company has already used its protein-folding AI, AlphaFold, to generate structures for the human proteome, as well as yeast, fruit flies, mice, and more. Back in December 2020, DeepMind took the ...

A multi-institute team led by St. Jude Children's Research Hospital and UT Southwestern Medical Center investigators ...

Much of our understanding of proteins in general is relative to their function in the human diet. To be sure, one of the major functions of protein in the human body is to provide the structural ...

A molecular “snapshot” of a protein can be critical to understanding its function. Scientists at Stanford and NYU have published and investigated a new structure of the protein LAG-3 which could ...