Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have identified a mechanism that protects the female brain from genetic diseases. Although one of the two X chromosomes is ...

Human sex chromosomes originated from a pair of autosomes, the ordinary or non-sex chromosomes that contain the majority of our genome and come in identical pairs. That ancestral pair of autosomes ...

X-chromosome inactivation varies across different areas of brains. Here, fluorescent imaging data from a mouse reveal where the father’s X chromosome is most active (white) and least active (blue). A ...

The cells of female mammals randomly inactivate one X chromosome to keep gene dosage the same as in males. Does it matter which X becomes inactive? Surprisingly, it does, according to new research ...

In a recent study published in the journal Nature Communications, researchers performed a meta-analysis of 908,697 samples to investigate the genetic, sex-dependent basis of kidney traits. Study: ...

About two-thirds of people with Alzheimer’s disease are women, yet due to the challenges in studying X chromosomes, a genetic foundation for this has been difficult to uncover. Now, two large ...

Each human cell contains 23 pairs of chromosomes that carry DNA within their nucleus. The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair. They determine the ...

Researchers from the University of California, San Francisco (UCSF) say they have now found that when the brain cells of female mice express only a maternal X chromosome, the animals’ memory and ...