Smallpox, which is caused by the variola virus of the Poxviridae family and the orthopoxvirus genus, is among the most devastating human diseases. It may have originated and spread from Egypt, the ...

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Subversion of host cell apoptosis is an important survival strategy for viruses to ensure their own proliferation and survival. Certain viruses express proteins homologous in sequence, structure and ...

Smallpox infection was often more severe in pregnant women than in non-pregnant women or in men, regardless of vaccination status. Women with smallpox infection during pregnancy have higher rates of ...

The cause of smallpox is the variola virus, which is an example of an exclusive anthroponotic agent. This infectious disease plagued global health from the earliest documented settlements through ...

Work published in the Proceedings of the National Academy of Sciences by Rosengard and colleagues helps to explain one way in which variola virus, the causative agent of smallpox, successfully evades ...

A cluster of variola viruses viewed under an electron microscope. Strains of the variola virus cause smallpox disease. Photo: © Callista Images/Corbis Smallpox was ...

The researchers hope these findings will settle a longstanding controversy and provide new insight into the history of one of humanity’s deadliest diseases. Until relatively recently, the earliest ...

This latest research suggests that smallpox is much more recent than we might think The oldest known sample of the smallpox-causing variola virus has been found within the DNA of a 17th-century child ...

The mpox virus is closely related to the smallpox virus (variola virus), which caused large, deadly outbreaks before it was eradicated by vaccination at the end of the 1970s. While the smallpox virus ...

DNA from a mummy buried under a church indicates the contagious and sometimes fatal disease may have struck much later than previously thought. Leslie Katz led a team that explored the intersection of ...