CtIP is a DNA end resection factor widely implicated in alternative end-joining (A-EJ)–mediated translocations in cell-based reporter systems. To address the physiological role of CtIP, an essential ...
Researchers have shown that harmful mutations present in the DNA play an important - yet neglected - role in the conservation and translocation programs of threatened species. Researchers in Lund, ...
Abnormalities in the structure of chromosomes within someone’s genetic makeup are called structural chromosomal abnormalities. Robertsonian translocations are very rare structural chromosomal ...
Antagonists of growth hormone-releasing hormone potentiate radiation response in prostate cancer. Background: A small subset of human lung cancer harbors the fusion of the gene for echinoderm ...
The SAVE regimen achieved an 86% ORR in newly diagnosed AML, with high MRD-negative rates, especially in NPM1 mutations or KMT2A rearrangements. Significant myelosuppression and infectious ...
Inherited retinal degeneration (IRD) encompasses various disorders characterized by progressive loss of retinal photoreceptor cells, ultimately leading to vision loss and blindness. Among the numerous ...
A multi-institution team of researchers led by scientists at Baylor College of Medicine has discovered a genetic signature that can identify drivers of poor outcomes in advanced estrogen-receptor ...
A combination of genetic mutations may explain the higher incidence of and poorer outcomes from pediatric leukemia in Hispanic and Latino children, according to Penn State College of Medicine ...
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Causes and Risk Factors of Multiple Myeloma
Multiple myeloma is a rare type of blood cancer that forms in plasma cells, a white blood cell that makes antibodies and ...
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