Purpose: To evaluate in vivo whether the expression of the human telomerase reverse transcriptase (hTERT) gene, the catalytic subunit of the telomerase complex, is predictive of response to ...

The study, published today in Cell, identified a small molecule compound that restores physiological levels of telomerase reverse transcriptase (TERT), which normally is repressed with the onset of ...

New Genetic Biomarker Flags Aggressive Brain Tumors. Clinicians typically classify meningiomas - the most common type of ...

Telomerase reverse transcriptase (TERT) is a well-known oncogene highly expressed in about 90% of all tumors, including hematological malignancies such as acute myeloid leukemia (AML), but targeting ...

RNA-based hTERT therapy may enhance telomere activity, improving lung cell health in pulmonary fibrosis (PF). Telomere dysfunction is a significant risk factor for PF, with telomerase reactivation ...