Researchers developed nanotechnology that selectively binds and degrades abnormal proteins. The technology shows promise for ...

Proteasomes are molecular machines for breaking down proteins. Drugmakers are working to coopt this process with targeted therapies. This story was originally published on BioPharma Dive. To receive ...

The Inducement Grant has an exercise price per share that is equal to the closing price of C4T’s common stock on the Grant Date. The Inducement Grant will vest over a four-year period, with 25% of the ...

What do you get when you insert a molecular glue degrader into an antibody-drug conjugate (ADC)? Fortitude Biomedicines is in ...

A Chinese research team has achieved a major advance in the precise regulation of protein degradation in living organisms, opening new avenues for therapeutic strategies against diseases ranging from ...

Targeted protein degradation has moved well beyond its prologue more than 20 years ago. 1 The number of publications describing different PROTACs (PROteolysis TArgeting Chimeras), molecular glues, and ...

Targeted protein degradation (TPD) is transforming drug discovery by leveraging the cell’s natural protein disposal systems to eliminate disease-causing proteins. Innovators are making rapid and ...

Targeted protein degradation is a therapeutic strategy that utilizes the cell’s natural machinery to eliminate disease-causing proteins. The field traces its origins to the development of thalidomide ...

Innovative Agents Highlight Growth of Targeted Protein Degradation Platform and BMS' Leadership in Innovative Cancer Therapies The latest data presented for the three lead CELMoD agents and BCL6 LDD ...

Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, ...

Enodia employs a large chemical space of inhibitors and a purpose-built library of signal-peptide cell lines.