Open-source software unlocks rapid DNA structure generation and analysis in one workflow

Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a comprehensive software suite to create accurate models of DNA in biomolecular ...
Phys.org

Study explores limits of DNA structure and function, may expand use of modified DNA in medicine

A team led by Professor Michal Hocek at IOCB Prague has explored the limits of the structure and function of DNA and successfully pushed forward known boundaries. Their latest research has just been ...
Phys.org

Researchers decode tertiary structure of DNA aptamer–ATP complex and improve binding affinity

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of their tertiary structures and binding mechanisms hinders their further ...

Missing DNA replication step revealed in first image of pre-initiation complex

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment has been the focus of a 30-year research question. New work from the Crick ...
PBS

The Discovery of DNA's Structure:

They were hardly modest, these two brash young scientists who in 1953 declared to patrons of the Eagle Pub in Cambridge, England, that they had "found the secret of life." But James Watson and Francis ...
Tech Xplore

Generative AI designs DNA origami to match user-drawn shapes automatically

A joint research team has developed an automated design technology that enables the creation of DNA origami structures that ...
ucdavis.edu

3D Genome Structure Guides Sperm Development

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...
Nature

DNA pioneer James Watson has died ― colleagues wrestle with his legacy

The co-discoverer of the structure of DNA helped to strengthen a US research institute and wrote a classic textbook, but also earned a reputation for racist and sexist comments. James Dewey Watson — ...
Kaleido Scope

What is DNA, and why it’s a key to understanding life, health, and disease: UAB experts explain how our DNA shapes who we are

DNA is often called the blueprint of life, but what does that really mean? Elizabeth Worthey, Ph.D., associate professor, Department of Genetics in the Heersink School of Medicine, explains everything ...
ExtremeTech

What Does DNA Stand For, and How Does It Work?

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...
Wall Street Journal

James Watson, Who Co-Discovered DNA Structure, Dies at 97

James Watson, the scientist who became famous for helping discover the structure of DNA in 1953 and notorious decades later for suggesting that Black people are intellectually inferior to whites, has ...