Pediatric acute myeloid leukemia (AML) is one of the most common acute leukemias in children. While treatment outcomes have ...

Genes contain the essential building instructions for life, guiding cells on which amino acids to assemble in what sequence to produce specific proteins. The human genome codes for about 20,000 such ...

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...

Human introns have extensively varying lengths. Previously, only U2AF-dependent splicing was known. Researchers from Fujita Health University now show that splicing in a subset of human short introns ...

A recent study highlights the pivotal role of alternative splicing in controlling plant secondary metabolism, which is crucial for producing bioactive compounds with significant medicinal and ...

Mechanism discovered that protects tissue after faulty gene expression Date: February 5, 2024 Source: University of Cologne Summary: A study has identified a protein complex that is activated by ...

In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...

– 53.7% mean splicing correction observed following a single 15 mg/kg dose of PGN-EDODM1, with all patients showing an improvement in splicing – – PGN-EDODM1 was generally well-tolerated at 15 mg/kg, ...