PURPOSE: To investigate, over a wide range of cumulative doxorubicin doses, the feasibility of using serum concentrations of cardiac troponin-T (cTnT) as a biomarker for doxorubicin-induced myocardial ...

What is the clinical value of a serum troponin level in a hemodynamically stable patient diagnosed with an acute pulmonary embolism (PE)? When combined with echocardiography in the emergency ...

Phase II trial of paclitaxel by 3-hour infusion as initial and salvage chemotherapy for metastatic breast cancer. Toxicity and efficacy of escalating dosages of recombinant human interleukin-6 after ...

High-dose cyclophosphamide (HD-CTX) is largely employed in high-dose chemotherapy (HD-CHT) protocols. HD-CTX dose-limiting toxicity expresses itself as cardiac toxicity which is fatal in a minority of ...

Chest pain and suspected myocardial infarction were the cause of about 5% of all emergency hospital admissions in 2017 to 2018. However, myocardial infarction will have occurred in only about 20% of ...

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Troponin refers to three different proteins that help regulate the contractions of the heart and skeletal muscles. Normal troponin levels range from 0 to 0.04 nanograms per milliliter (ng/ml). The ...

A 71-year-old woman was assessed before undergoing a vaginal hysterectomy, bilateral salpingo-oophrectomy and pelvic lymph node dissection for stage I endometrial cancer. She had experienced a ...

Using age-specific thresholds for troponin measurement would more accurately diagnose myocardial injury when assessing patients for suspected myocardial infarction (MI), a new study suggests. The ...

1 Department of Health Sciences, University of Jaén, E-23071 Jaén, Spain 2 Basic Cardiovascular Research Section, Department of Morphological Sciences, School of Medicine, University of Granada, ...