The 5’ cap structure exerts profound impacts on mRNA vaccine stability, translational efficiency, and evasion of innate immunity, encompassing key enzymatic components: triphosphatase (TPase), ...

Next, we investigated the impact of the length of capped branched strands (Fig. 2c and Supplementary Table 1a; CircR3, CircR5 and CircR7). Among the lengths tested (1 nt, 6 nt and 12 nt), 6-mer ...

The cold season is in full swing, throats are scratchy and noses are running. We feel ill and hope it is not the flu. The influenza virus continues to pose a threat to our health. It triggers seasonal ...

As RNA therapeutics evolve far beyond their vaccine origins, a new generation of scientists and manufacturers is rethinking how to produce these complex medicines safely, efficiently, and at scale.

This article is based on a poster originally authored by Harrison H, Glen A , Andrews B, Bayle E, Duncan C, Fyfe M , Guest P, Rausch O , Swain C, Thomas B, Zemla-Brown A, Baric R, Chen Y, Froggatt H, ...