An error in protein conformation can lead to disease. What are the genetic and molecular causes for incorrectly formed proteins? molecules. In 1917 the German chemist ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The "mini prion" folds and stacks ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The “mini prion” folds and stacks ...

AMES, Iowa – Iowa State University researchers have described with single-molecule precision how copper ions cause prion proteins to misfold and seed the misfolding and clumping of nearby prion ...

When proteins are made in a cell, they start out as strings of amino acids, which have to be folded into the correct, three-dimensional shape so they will function properly. Misfolded proteins can ...

For the first time, therapeutically effective medications are now available for Alzheimer's disease. Effective symptomatic ...

Neurodegenerative diseases form a tangled biological web with overlapping molecular signatures and symptoms. To decode this complexity, a multi-institute collaboration led by St. Jude Children's ...

The first synthetic fragment of tau protein has been created, revealing more about the diagnosis and treatment of neurodegenerative diseases. Researchers at Northwestern University (IL, USA) and the ...

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's ...

Alpha1-antitrypsin deficiency, an inherited disorder affecting 100,000 people in the U.S., causes a progressive and incurable ...

The brain of a rat in which a fluorescent protein has been used to highlight transplanted human brain cells - Copyright Stanford University/AFP Sergiu PASCA The brain ...