The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. Researchers ...

Researchers have created a human-derived neuromuscular junction from a person with amyotrophic lateral sclerosis (ALS) with the goal of testing anti-ALS drugs that not only prevent neuronal death but ...

The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes. A skeletal muscle isn’t much use without a ...

A research group from the Sackler Faculty of Medicine and the Sagol School of Neuroscience at Tel Aviv University uncovered, for the first time, the biological mechanism causing nerve destruction in ...

An international research team led by a University of Ottawa Faculty of Medicine investigator has revealed ultra-detailed intricacies in how nerve signals activate at the neuromuscular junction, a ...

Findings published in The American Journal of Pathology identify GLUD1 enzyme as a potential therapeutic target for muscle restoration through metabolic reprogramming, addressing clinically unmet need ...