TMEM63B, a mechanosensitive lipid scramblase, has an autoinhibitory domain in its C-terminal tail that helps keep it inactive ...

An autoinhibitory domain in the C-terminal tail of the TMEM63B, a mechanosensitive lipid scramblase, helps maintain its ...

Our cells' membranes have many functions. They not only provide mechanical protection but also precisely control which ...

Collaboration between researchers at the University of Geneva, Institut de biologie structurale de Grenoble, and the University of Fribourg has shown how lipids and proteins in cell membranes react in ...

A long-standing mystery at the heart of a devastating childhood neurodegenerative disorder has finally begun to yield its secrets. In a study published in Nature Cell Biology, researchers report that ...

Weill Cornell Medicine investigators have determined the mechanism by which a molecule within cells can help tune the light ...

BUFFALO, N.Y. – In cell biology, the membrane is made of two layers of lipids that are often unevenly distributed. Scientists know this asymmetry affects how membranes perform important tasks like ...

Scientists build the first 3D "Lipid Brain Atlas," defining 539 chemical zones ("lipizones") and revealing white matter is a patchwork of distinct biochemical zones.

Edward Lyman, associate professor in the departments of physics and astronomy, as well as chemistry and biochemistry, was recently published in the journal Nature Chemical Biology. The article, “When ...

The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place. This membrane protects the cell from its surroundings and divides it into ...

S-palmitoylation, a reversible lipid-based post-translational modification, is notably elevated in colorectal cancer (CRC) due to common lipid metabolism disorders. It has been reported to play ...