Starting iron chelation therapy early may prevent growth problems and organ damage from iron overload in children with TDT. Currently approved medications have limitations for use in very young ...

Patients on dopaminergic agonists (n, mean daily L-dopa equivalent in mg) 18 (243) 18 (220) 4 (225) 13 (250) Patients on L-dopa and agonists (n) 7 7 2 5 Cognition and behavior: MDS-UPDRS part I score ...

Myelodysplastic syndromes (MDS) often require frequent blood transfusions for anemia, which can lead to iron overload. Over time, extra iron can damage organs throughout the body. Underlying MDS ...

An iron-binding drug that is already approved for treatment of other diseases could provide a novel way to attack ovarian tumors, according to a new study led by Weill Cornell Medicine researchers.

New evidence suggests that trapping iron in unusable forms may starve vulnerable neurons, challenging decades of thinking about iron toxicity in Parkinson’s disease and opening new therapeutic ...

Iron-chelating drugs bind tightly to iron, preventing cells from using it. To confirm the importance of iron in ovarian cancer, Dr. Cubillos-Ruiz's team first looked at a collection of human tumor ...

Researchers at the University of São Paulo (USP) in Brazil have discovered that two osteoporosis drugs (etidronate and tiludronate) may combat diseases caused by iron accumulation in the body. In ...

Longitudinal survey data from Mexico suggested that a so-called weekend warrior physical activity pattern was associated with a reduced risk of mild dementia. (British Journal of Sports Medicine) Also ...