Cilk1 deficiency disrupts normal tooth development by altering primary cilia function and weakening Hedgehog signaling. This reduction triggers extra diastemal teeth, enlarges them under further ...
A hypothetical model illustrating how reduced Hedgehog signaling alters interactions between the rudimentary tooth bud (R2) and the first molar (M1), leading to supernumerary (SN) tooth or molar ...
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