Fluorescence molecular imaging (FMI) is becoming a powerful tool to improve surgical precision and diagnostics. Although significant advances have been made in imaging technology and contrast agents, ...

Autofluorescence (AF) is a prevalent issue in immunofluorescence (IF) microscopy that arises from endogenous biomolecules such as collagen, flavins, and lipofuscin 1,2. The presence of ...

Limits of patch-based training However, most existing studies follow practices from natural-image processing by randomly cropping large images into small patches, typically 128×128 pixels, for data ...

Peking University, June 9, 2026: Recent years have witnessed great advances in applying deep learning to improve fluorescence microscopy imaging. However, enhancing the fidelity of image restoration ...