Obesity is a metabolic disorder tied to endothelial dysfunction and increased risk of cardiovascular disease. A recent study, published in the journal Function, investigated the mechanisms responsible ...

Pre-eclampsia (PE) is a clinical syndrome of maternal endothelial dysfunction manifesting with elevated blood pressure and ...

IRI is a shared pathological process in myocardial infarction, ischaemic stroke, acute kidney injury, lung injury, and graft dysfunction after transplantation.

Hypertension (also referred to as high blood pressure [HBP]) is the foremost cause, and a preventable significant risk factor, of cardiovascular disease (CVD) and premature death worldwide [1].

Endothelial dysfunction represents a major cardiovascular risk factor for hypertension. Sp1 and Sp3 belong to the specificity protein and Krüppel-like transcription factor families. They are ...

Sepsis, a life-threatening systemic inflammatory response triggered by infection, has long challenged clinicians with its persistently high mortality (up to 40-50% in septic shock). At the heart of ...