Why does ALS pathology spread differently among patients?

A research team at the Brain Research Institute, Niigata University has found that APOE ε4, a genetic factor best known for ...
Hosted on MSN

ALS may stem partly from failed protein cleanup in motor neurons

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes the progressive loss of motor neurons, which in most cases leads to respiratory failure within three to five years after ...
Neuroscience News

Alzheimer’s Risk Gene May Drive Aggressive ALS

The Alzheimer's risk gene APOE ε4 drives the aggressive, brain-wide Type 2 subtype of ALS, causing cognitive decline.
Medical Xpress

Gene therapy may slow loss of motor function in ALS

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating ...
Rolling Out

Failed ALS trials reveal major medical breakthrough

When the results of the first-ever platform trial for amyotrophic lateral sclerosis (ALS) were published this February, the headlines might have seemed disappointing: four experimental drugs failed to ...
Business Wire

VectorY Therapeutics Receives FDA Clearance of IND to Proceed with the PIONEER-ALS Phase 1/2 Trial of VTx-002, a First-in-Class Vectorized Antibody Targeting TDP-43 Pathology ...

AMSTERDAM & BOSTON--(BUSINESS WIRE)--VectorY Therapeutics, a leader in vectorized antibody therapies for neurodegenerative diseases, announced today that the U.S. Food and Drug Administration (FDA) ...