A new perspective published in Nature Reviews Drug Discovery examines the potential of biomolecular condensates to transform drug discovery. Condensates are membrane-less organelles that form ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

A research group led by Professor Hiroaki SUZUKI and Takeshi HAYAKAWA from the Faculty of Science and Engineering at Chuo University, graduate student Zhitai HUANG, graduate students Kanji KANEKO (at ...

For decades, cancer research has focused on the dysregulation of various cellular pathways, including transcription, chromatin structure, proliferative signaling, RNA processing, and genomic integrity ...

Biomolecular condensates are membraneless hubs of condensed proteins and nucleic acids within cells, which researchers are realizing are tied to an increasing number of cellular processes and diseases ...