On April 14, 2003, the National Institutes of Health issued a press release announcing that the Human Genome Project had been completed ahead of schedule and under budget. At the time, the human ...

Whether on the patio with a cool summer breeze or gathered around a coffee table by the fire on a chilly night, there’s something special about game night with loved ones. Until, of course, you can’t ...

Sequence-based protein function and structure prediction depends crucially on sequence-search sensitivity and accuracy of the resulting sequence alignments. We present an open-source, general-purpose ...

Multiple sequence alignment (MSA) lies at the heart of comparative genomics, structural biology and evolutionary inference. By arranging three or more nucleotide or amino acid sequences in a matrix, ...