Disrupted lipid metabolism in the central nervous system triggers α-Syn aggregation, ferroptosis, mitochondrial dysfunction, and neuroinflammation. All of these contribute to the onset and progression ...

To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...

ESC Huge Decreases in LDL Cholesterol With Alirocumab: ODYSSEY Tested in high-risk CVD patients, heterozygous-FH patients, and patients intolerant to statins, treatment with alirocumab resulted in as ...

This review paper summarizes numerous research studies that address the role of kidney cholesterol and lipid accumulation in the development and progression of chronic kidney disease (CKD). ZyVersa’s ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

Please provide your email address to receive an email when new articles are posted on . There is not yet enough evidence to adequately assess the benefit-harm balance of screening for lipid disorders ...

New review shows statins remain first-line therapy in MASLD, while PCSK9 inhibitors offer potential but require more evidence. Learn more about evolving treatment guidance.

New Statement Addresses CV Disease in Type 1 Diabetes A new joint statement from the American Heart Association and American Diabetes Association summarizes evidence regarding CVD in type 1 diabetes ...